Glucosamine

Glucosamine Molecule
Glucosamine (often marketed as the sulphated derivative) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. Glucosamine is part of the structure of chitosan and chitin, complex polysaccharides that comprise the exoskeletons of crustaceans (crabs, prawns, shrimp and the like). Glucosamine is usually manufactured commercially by the hydrolysis of such crustacean exoskeletons.
Glucosamine is one of the most common non-vitamin, non-mineral, dietary supplements used by adults. Because glucosamine is a precursor in the synthesis of glycosaminoglycans (e.g. chondroitin sulphate), that represent important constituents of joint cartilage, dietary supplements containing glucosamine may be effective in limiting cartilage breakdown and eleviating the effects of osteoarthritis.
Animal and clinical studies reporting beneficial effects have used glucosamine sulphate, sometimes in conjuction with chondroitin sulphate that may increase efficacy1.
A large, 3-year, placebo-controlled clinical trial in Europe showed that glucosamine sulphate supplementation had a clear benefit in reducing the effects of osteoarthritis2.
Glucosamine sulphate from New Vision Biotech is supplied as a white, free-flowing powder (approx. 60 mesh) and is available in 5, 10 and 20 kg bags. Bulk quantity (>200 kg/order) discounts apply.
- Dahmer S, Schiller RM (August 2008). “Glucosamine”. Am Fam Physician 78: 471–476; Herrero-Beaumont G, Ivorra JA, Del Carmen Trabado M, et al. (February 2007). “Glucosamine sulfate in the treatment of knee osteoarthritis symptoms: A randomized, double-blind, placebo-controlled study using acetaminophen as a side comparator”. Arthritis Rheum. 56: 555–567.
- Reginster JY, Deroisy R, Rovati LC, et al. (January 2001). “Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial”. Lancet 357: 251–256; Pavelká K, Gatterová J, Olejarová M, Machacek S, Giacovelli G, Rovati LC (October 2002). “Glucosamine sulfate use and delay of progression of knee osteoarthritis: a 3-year, randomized, placebo-controlled, double-blind study”. Arch. Internal Med. 162: 2113–2123
